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AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epith...

AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epith...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_366295412

AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epithelial Cells

About this item

Full title

AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epithelial Cells

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory cell and molecular biology, 2010-06, Vol.42 (6), p.676-684

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

The metabolic sensor AMP-activated kinase (AMPK) inhibits both the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) Cl(-) channel and epithelial Na(+) channel (ENaC), and may inhibit secretion of proinflammatory cytokines in epithelia. Here we have tested in primary polarized CF and non-CF human bronchial epithelial (HBE) cells the e...

Alternative Titles

Full title

AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epithelial Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_366295412

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_366295412

Other Identifiers

ISSN

1044-1549

E-ISSN

1535-4989

DOI

10.1165/2009-0147OC

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