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A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed c...

A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_613950601

A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin’s lymphoma

About this item

Full title

A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin’s lymphoma

Publisher

Germany: Springer Nature B.V

Journal title

Annals of hematology, 2006-05, Vol.85 (5), p.301-307

Language

English

Formats

Publication information

Publisher

Germany: Springer Nature B.V

More information

Scope and Contents

Contents

In an attempt to exploit bcl-2 overexpression and aberrant p53 function, two frequently encountered aberrations that predict marked treatment resistance and worse prognosis in patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL), we combined theophylline, pentostatin, and chlorambucil at two dose levels (cohort I: 30 mg...

Alternative Titles

Full title

A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin’s lymphoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_613950601

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_613950601

Other Identifiers

ISSN

0939-5555

E-ISSN

1432-0584

DOI

10.1007/s00277-005-0025-9

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