Lack of effect of dalcetrapib on QT interval in healthy subjects following multiple dosing
Lack of effect of dalcetrapib on QT interval in healthy subjects following multiple dosing
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Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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English
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Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Purpose Evaluate dalcetrapib's potential to prolong QT intervals in healthy subjects. Methods This was a single-center, randomized, active and placebo-controlled, six-sequence, three-period cross-over study. Participants [18-65 years; body mass index (BMI) 18-30 kg/m²] were randomized to daily doses of dalcetrapib 600 mg (therapeutic) or 3,900 mg (...
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Full title
Lack of effect of dalcetrapib on QT interval in healthy subjects following multiple dosing
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TN_cdi_proquest_journals_633058998
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_633058998
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ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-010-0841-2