Downregulation of Cystine Transporter xc– by Irinotecan in Human Head and Neck Cancer FaDu Xenograft...
Downregulation of Cystine Transporter xc– by Irinotecan in Human Head and Neck Cancer FaDu Xenografts
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Basel, Switzerland: S. Karger AG
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English
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Basel, Switzerland: S. Karger AG
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Background: The purpose of this study was: (1) to document the critical requirement of cystine for growth of human tumor cells in vitro, and (2) to determine the effect of the anticancer agent irinotecan on the cystine transporter x c – in head and neck FaDu xenografts. Methods: Cell growth was measured by sulforhodamine B assay. xCT protein, gluta...
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Downregulation of Cystine Transporter xc– by Irinotecan in Human Head and Neck Cancer FaDu Xenografts
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TN_cdi_proquest_journals_645274628
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_645274628
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ISSN
0009-3157,1421-9794
E-ISSN
1421-9794
DOI
10.1159/000316334