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Downregulation of Cystine Transporter xc– by Irinotecan in Human Head and Neck Cancer FaDu Xenograft...

Downregulation of Cystine Transporter xc– by Irinotecan in Human Head and Neck Cancer FaDu Xenograft...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_645274628

Downregulation of Cystine Transporter xc– by Irinotecan in Human Head and Neck Cancer FaDu Xenografts

About this item

Full title

Downregulation of Cystine Transporter xc– by Irinotecan in Human Head and Neck Cancer FaDu Xenografts

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Chemotherapy (Basel), 2010-01, Vol.56 (3), p.223-233

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Background: The purpose of this study was: (1) to document the critical requirement of cystine for growth of human tumor cells in vitro, and (2) to determine the effect of the anticancer agent irinotecan on the cystine transporter x c – in head and neck FaDu xenografts. Methods: Cell growth was measured by sulforhodamine B assay. xCT protein, gluta...

Alternative Titles

Full title

Downregulation of Cystine Transporter xc– by Irinotecan in Human Head and Neck Cancer FaDu Xenografts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_645274628

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_645274628

Other Identifiers

ISSN

0009-3157,1421-9794

E-ISSN

1421-9794

DOI

10.1159/000316334

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