Log in to save to my catalogue

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's d...

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_741865476

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

About this item

Full title

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (31), p.13888-13893

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Alzheimer's disease (AD) brains are characterized by amyloid-β-containing plaques and hyperphosphorylated tau-containing neurofibrillary tangles (NFTs); however, in frontotemporal dementia, the tau pathology manifests in the absence of overt amyloid-β plaques. Therapeutic strategies so far have primarily been targeting amyloid-β, although those tar...

Alternative Titles

Full title

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_741865476

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_741865476

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1009038107

How to access this item