Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients wit...
Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients with advanced solid tumors
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Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Language
English
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Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Purpose The aim of this study was to investigate the safety and pharmacokinetics of motesanib (AMG 706), a small-molecule antagonist of vascular endothelial growth factor receptors 1, 2, and 3, platelet-derived growth factor receptor, and c-Kit in Japanese patients with advanced solid tumors. Methods Patients were administered motesanib orally once...
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Full title
Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients with advanced solid tumors
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TN_cdi_proquest_journals_746480033
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_746480033
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ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-010-1243-y