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Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients wit...

Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients wit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_746480033

Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients with advanced solid tumors

About this item

Full title

Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients with advanced solid tumors

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

Journal title

Cancer chemotherapy and pharmacology, 2010-10, Vol.66 (5), p.935-943

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

Purpose The aim of this study was to investigate the safety and pharmacokinetics of motesanib (AMG 706), a small-molecule antagonist of vascular endothelial growth factor receptors 1, 2, and 3, platelet-derived growth factor receptor, and c-Kit in Japanese patients with advanced solid tumors. Methods Patients were administered motesanib orally once...

Alternative Titles

Full title

Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients with advanced solid tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_746480033

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_746480033

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-010-1243-y

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