Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organ...
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The origin recognition complex (ORC) is a DNA replication initiator protein also known to be involved in diverse cellular functions including gene silencing, sister chromatid cohesion, telomere biology, heterochromatin localization, centromere and centrosome activity, and cytokinesis. We show that, in human cells, multiple ORC subunits associate wi...
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Full title
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization
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TN_cdi_proquest_journals_747958051
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_747958051
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1009945107
