Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis
Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Toll-like receptors (TLRs) are innate immune receptors that have recently emerged as regulators of neuronal survival and developmental neuroplasticity. Adult TLR3-deficient mice exhibited enhanced hippocampus-dependent working memory in the Morris water maze, novel object recognition, and contextual fear-conditioning tasks. In contrast, TLR3-defici...
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Full title
Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis
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TN_cdi_proquest_journals_749480975
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_749480975
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1005807107
