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Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions

Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_756172999

Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions

About this item

Full title

Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions

Publisher

Netherlands: Springer Nature B.V

Journal title

Molecular and cellular biochemistry, 2001-06, Vol.222 (1-2), p.199

Language

English

Formats

Publication information

Publisher

Netherlands: Springer Nature B.V

More information

Scope and Contents

Contents

While Cr (VI)-containing compounds are well established carcinogens, the mechanisms of their action remain to be investigated. In this study we show that Cr (VI) causes increased tyrosine phosphorylation in human lung epithelial A549 cells in a time-dependent manner. N-acetyl-cysteine (NAC), a general antioxidant, inhibited Cr (VI)-induced tyrosine...

Alternative Titles

Full title

Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_756172999

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_756172999

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1023/A:1017926531890

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