Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions
Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions
About this item
Full title
Author / Creator
Qian, Y , Jiang, B H , Flynn, D C , Leonard, S S , Wang, S , Zhang, Z , Ye, J , Chen, F , Wang, L and Shi, X
Publisher
Netherlands: Springer Nature B.V
Journal title
Language
English
Formats
Publication information
Publisher
Netherlands: Springer Nature B.V
Subjects
More information
Scope and Contents
Contents
While Cr (VI)-containing compounds are well established carcinogens, the mechanisms of their action remain to be investigated. In this study we show that Cr (VI) causes increased tyrosine phosphorylation in human lung epithelial A549 cells in a time-dependent manner. N-acetyl-cysteine (NAC), a general antioxidant, inhibited Cr (VI)-induced tyrosine...
Alternative Titles
Full title
Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_756172999
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_756172999
Other Identifiers
ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1023/A:1017926531890