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Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments withou...

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments withou...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_803688772

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting A[beta] and tau pathologies in 3xTg-AD mice

About this item

Full title

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting A[beta] and tau pathologies in 3xTg-AD mice

Publisher

Heidelberg: Springer Nature B.V

Journal title

Acta neuropathologica, 2010-11, Vol.120 (5), p.605

Language

English

Formats

Publication information

Publisher

Heidelberg: Springer Nature B.V

More information

Scope and Contents

Contents

In addition to the occurrence of numerous neurofibrillary tangles and Aβ plaques, neurogenesis and neuronal plasticity are markedly altered in Alzheimer disease (AD). Although the most popular therapeutic approach has been to inhibit neurodegeneration, another is to promote neurogenesis and neuronal plasticity by utilizing the regenerative capacity...

Alternative Titles

Full title

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting A[beta] and tau pathologies in 3xTg-AD mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_803688772

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_803688772

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-010-0734-6

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