Role of chronic ryanodine receptor phosphorylation in heart failure and [Beta]-adrenergic receptor b...
Role of chronic ryanodine receptor phosphorylation in heart failure and [Beta]-adrenergic receptor blockade in mice
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Ann Arbor: American Society for Clinical Investigation
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Language
English
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Ann Arbor: American Society for Clinical Investigation
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Increased sarcoplasmic reticulum (SR) Ca2+ leak via the cardiac ryanodine receptor/calcium release channel (RyR2) is thought to play a role in heart failure (HF) progression. Inhibition of this leak is an emerging therapeutic strategy. To explore the role of chronic PKA phosphorylation of RyR2 in HF pathogenesis and treatment, we generated a knocki...
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Role of chronic ryanodine receptor phosphorylation in heart failure and [Beta]-adrenergic receptor blockade in mice
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TN_cdi_proquest_journals_817461607
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_817461607
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ISSN
0021-9738
E-ISSN
1558-8238
