Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmac...
Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach
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New Zealand: Springer Nature B.V
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English
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New Zealand: Springer Nature B.V
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Sugammadex is a γ-cyclodextrin that binds with high affinity to the neuromuscular blocking agents (NMBAs) rocuronium (bromide) and vecuronium (bromide) by encapsulation. Cyclodextrins are known to form inclusion complexes with other compounds.
We utilized a previously developed pharmacokinetic-pharmacodynamic model to identify potential clinical...
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Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach
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TN_cdi_proquest_journals_817471506
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_817471506
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ISSN
1173-2563
E-ISSN
1179-1918
DOI
10.2165/11584730-000000000-00000