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Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmac...

Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_817471506

Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach

About this item

Full title

Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach

Publisher

New Zealand: Springer Nature B.V

Journal title

Clinical drug investigation, 2011, Vol.31 (2), p.101

Language

English

Formats

Publication information

Publisher

New Zealand: Springer Nature B.V

More information

Scope and Contents

Contents

Sugammadex is a γ-cyclodextrin that binds with high affinity to the neuromuscular blocking agents (NMBAs) rocuronium (bromide) and vecuronium (bromide) by encapsulation. Cyclodextrins are known to form inclusion complexes with other compounds.
We utilized a previously developed pharmacokinetic-pharmacodynamic model to identify potential clinical...

Alternative Titles

Full title

Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_817471506

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_817471506

Other Identifiers

ISSN

1173-2563

E-ISSN

1179-1918

DOI

10.2165/11584730-000000000-00000

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