Activation and intrinsic [gamma]-secretase activity of presenilin 1
Activation and intrinsic [gamma]-secretase activity of presenilin 1
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Publisher
Washington: National Academy of Sciences
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Language
English
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Publisher
Washington: National Academy of Sciences
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Contents
A complex composed of presenilin (PS), nicastrin, PEN-2, and APH-1 is absolutely required for ...-secretase activity in vivo. Evidence has emerged to suggest a role for PS as the catalytic subunit of ...-secretase, but it has not been established that PS is catalytically active in the absence of associated subunits. We now report that bacterially s...
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Full title
Activation and intrinsic [gamma]-secretase activity of presenilin 1
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TN_cdi_proquest_journals_818647022
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_818647022
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ISSN
0027-8424
E-ISSN
1091-6490
