Prognostic value of PIK3CA and phosphorylated AKT expression in ovarian cancer
Prognostic value of PIK3CA and phosphorylated AKT expression in ovarian cancer
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Publisher
Berlin: Springer
Journal title
Language
English
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Publisher
Berlin: Springer
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Scope and Contents
Contents
Disrupted phosphatidylinositol 3-kinase (PI3K) activity and its effect on the downstream target AKT plays an important role in malignant diseases. Gain and/or amplification of PIK3CA gene, encoding the catalytic subunit of phosphatidylinositol 3-kinase (p110 alpha) and its increased expression are associated with enhanced PI3K activity in ovarian c...
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Full title
Prognostic value of PIK3CA and phosphorylated AKT expression in ovarian cancer
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TN_cdi_proquest_journals_820699145
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_820699145
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ISSN
0945-6317
E-ISSN
1432-2307
DOI
10.1007/s00428-006-0358-3
