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Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, l...

Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, l...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_821290398

Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice

About this item

Full title

Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (51), p.22272-22277

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Both deficiency and excess of growth hormone (GH) are associated with increased mortality and morbidity. GH replacement in otherwise healthy subjects leads to complications, whereas individuals with isolated GH deficiency such as Laron dwarfs show increased life span. Here, we determined the effects of treatment with the GH-releasing hormone (GHRH)...

Alternative Titles

Full title

Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_821290398

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_821290398

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1016369107

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