Airway Epithelial Indoleamine 2,3-Dioxygenase Inhibits CD4^sup +^ T Cells during Aspergillus fumigat...
Airway Epithelial Indoleamine 2,3-Dioxygenase Inhibits CD4^sup +^ T Cells during Aspergillus fumigatus Antigen Exposure
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Author / Creator
Paveglio, Sara A , Allard, Jenna , Hodgkins, Samantha R Foster , Ather, Jennifer L , Bevelander, Mieke , Campbell, Jana Mayette , LeClair, Laurie A Whittaker , McCarthy, Sean M , van der Vliet, Albert , Suratt, Benjamin T , Boyson, Jonathan E , Uematsu, Satoshi , Akira, Shizuo and Poynter, Matthew E
Publisher
New York: American Thoracic Society
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Language
English
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Publisher
New York: American Thoracic Society
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Contents
Indoleamine 2,3-dioxygenase (IDO) suppresses the functions of CD4(+) T cells through its ability to metabolize the essential amino acid tryptophan. Although the activity of IDO is required for the immunosuppression of allergic airway disease by the Toll-Like-Receptor 9 (TLR9) agonist, oligonucleotides comprised of cytosine and guanine nucleotides l...
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Full title
Airway Epithelial Indoleamine 2,3-Dioxygenase Inhibits CD4^sup +^ T Cells during Aspergillus fumigatus Antigen Exposure
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TN_cdi_proquest_journals_847664777
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_847664777
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E-ISSN
1535-4989
