Effects of Nilotinib on Single-Dose Warfarin Pharmacokinetics and Pharmacodynamics: A Randomized, Si...
Effects of Nilotinib on Single-Dose Warfarin Pharmacokinetics and Pharmacodynamics: A Randomized, Single-Blind, Two-Period Crossover Study in Healthy Subjects
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Publisher
Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Background and Objective
: Nilotinib (Tasigna®), a highly selective and potent BCR-ABL tyrosine kinase inhibitor, is approved for the treatment of chronic myeloid leukaemia in the chronic phase (CML-CP) and the accelerated phase (CML-AP) in patients resistant or intolerant to prior therapy, including imatinib. Nilotinib has shown competitive inh...
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Full title
Effects of Nilotinib on Single-Dose Warfarin Pharmacokinetics and Pharmacodynamics: A Randomized, Single-Blind, Two-Period Crossover Study in Healthy Subjects
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TN_cdi_proquest_journals_848725200
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_848725200
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ISSN
1173-2563
E-ISSN
1179-1918
DOI
10.2165/11538700-000000000-00000
