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Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transien...

Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transien...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_853704084

Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons

About this item

Full title

Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (8), p.3371-3376

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Despite its clinical importance, the mechanisms that mediate or generate itch are poorly defined. The identification of pruritic compounds offers insight into understanding the molecular and cellular basis of itch. Imiquimod (IQ) is an agonist of Toll-like receptor 7 (TLR7) used to treat various infectious skin diseases such as genital warts, kerat...

Alternative Titles

Full title

Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_853704084

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_853704084

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1019755108

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