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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_856589361

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Microtubules have pivotal roles in fundamental cellular processes and are targets of antitubulin chemotherapeutics
1
. Microtubule-targeted agents such as Taxol and vincristine are prescribed widely for various malignancies, including ovarian and breast adenocarcinomas, non-small-cell lung cancer, leukaemias and lymphomas
1
. These agen...

Alternative Titles

Full title

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_856589361

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_856589361

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature09779

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