Discovery and characterization of a unique mycobacterial heme acquisition system
Discovery and characterization of a unique mycobacterial heme acquisition system
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Mycobacterium tuberculosis must import iron from its host for survival, and its siderophore-dependent iron acquisition pathways are well established. Here we demonstrate a newly characterized pathway, whereby M. tuberculosis can use free heme and heme from hemoglobin as an iron source. Significantly, we identified the genomic region, Rv0202c-Rv0207...
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Discovery and characterization of a unique mycobacterial heme acquisition system
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TN_cdi_proquest_journals_858457319
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_858457319
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1009516108