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Discovery and characterization of a unique mycobacterial heme acquisition system

Discovery and characterization of a unique mycobacterial heme acquisition system

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_858457319

Discovery and characterization of a unique mycobacterial heme acquisition system

About this item

Full title

Discovery and characterization of a unique mycobacterial heme acquisition system

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (12), p.5051-5056

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Mycobacterium tuberculosis must import iron from its host for survival, and its siderophore-dependent iron acquisition pathways are well established. Here we demonstrate a newly characterized pathway, whereby M. tuberculosis can use free heme and heme from hemoglobin as an iron source. Significantly, we identified the genomic region, Rv0202c-Rv0207...

Alternative Titles

Full title

Discovery and characterization of a unique mycobacterial heme acquisition system

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_858457319

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_858457319

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1009516108

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