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c-Jun N-Terminal Kinase 1 Promotes Transforming Growth Factor-[Beta]1-Induced Epithelial-to-Mesenchy...

c-Jun N-Terminal Kinase 1 Promotes Transforming Growth Factor-[Beta]1-Induced Epithelial-to-Mesenchy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_862339093

c-Jun N-Terminal Kinase 1 Promotes Transforming Growth Factor-[Beta]1-Induced Epithelial-to-Mesenchymal Transition via Control of Linker Phosphorylation and Transcriptional Activity of Smad3

About this item

Full title

c-Jun N-Terminal Kinase 1 Promotes Transforming Growth Factor-[Beta]1-Induced Epithelial-to-Mesenchymal Transition via Control of Linker Phosphorylation and Transcriptional Activity of Smad3

Publisher

New York: American Thoracic Society

Journal title

American journal of respiratory cell and molecular biology, 2011-04, Vol.44 (4), p.571

Language

English

Formats

Publication information

Publisher

New York: American Thoracic Society

More information

Scope and Contents

Contents

Transforming growth factor (TGF)-β1 is a key mediator of lung remodeling and fibrosis. Epithelial cells are both a source of and can respond to TGF-β1 with epithelial-to-mesenchymal transition (EMT). We recently determined that TGF-β1-induced EMT in lung epithelial cells requires the presence of c-Jun N-terminal kinase (JNK) 1. Because TGF-β1 signa...

Alternative Titles

Full title

c-Jun N-Terminal Kinase 1 Promotes Transforming Growth Factor-[Beta]1-Induced Epithelial-to-Mesenchymal Transition via Control of Linker Phosphorylation and Transcriptional Activity of Smad3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_862339093

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_862339093

Other Identifiers

E-ISSN

1535-4989

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