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Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protectiv...

Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protectiv...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_866421871

Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells

About this item

Full title

Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (19), p.7914-7919

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Vaccines can greatly reduce the spread of and deaths from many infectious diseases. However, many infections have no successful vaccines. Better understanding of the generation of protective CD8 memory T cells by vaccination is essential for the rational design of new vaccines that aim to prime cellular immune responses. Here we demonstrate that th...

Alternative Titles

Full title

Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_866421871

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_866421871

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1104588108

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