Early Cyst Growth Is Associated with the Increased Nuclear Expression of Cyclin D1/Rb Protein in an...
Early Cyst Growth Is Associated with the Increased Nuclear Expression of Cyclin D1/Rb Protein in an Autosomal-Recessive Polycystic Kidney Disease Rat Model
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Basel: S. Karger AG
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English
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Basel: S. Karger AG
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Background: In this study we hypothesised that proliferation, and the increased expression of G1-phase cyclins (D1, E) and phosphorylated retinoblastoma protein (p-Rb) is restricted to the early period of synchronized cyst growth in autosomal-recessive polycystic kidney disease (ARPKD). Methods: Lewis polycystic kidney disease (lpk) rats (model of...
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Early Cyst Growth Is Associated with the Increased Nuclear Expression of Cyclin D1/Rb Protein in an Autosomal-Recessive Polycystic Kidney Disease Rat Model
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TN_cdi_proquest_journals_878642548
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_878642548
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1660-8151
E-ISSN
2235-3186
DOI
10.1159/000320149