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Early Cyst Growth Is Associated with the Increased Nuclear Expression of Cyclin D1/Rb Protein in an...

Early Cyst Growth Is Associated with the Increased Nuclear Expression of Cyclin D1/Rb Protein in an...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_878642548

Early Cyst Growth Is Associated with the Increased Nuclear Expression of Cyclin D1/Rb Protein in an Autosomal-Recessive Polycystic Kidney Disease Rat Model

About this item

Full title

Early Cyst Growth Is Associated with the Increased Nuclear Expression of Cyclin D1/Rb Protein in an Autosomal-Recessive Polycystic Kidney Disease Rat Model

Publisher

Basel: S. Karger AG

Journal title

Nephron, 2011-04, Vol.117 (4), p.e93

Language

English

Formats

Publication information

Publisher

Basel: S. Karger AG

More information

Scope and Contents

Contents

Background: In this study we hypothesised that proliferation, and the increased expression of G1-phase cyclins (D1, E) and phosphorylated retinoblastoma protein (p-Rb) is restricted to the early period of synchronized cyst growth in autosomal-recessive polycystic kidney disease (ARPKD). Methods: Lewis polycystic kidney disease (lpk) rats (model of...

Alternative Titles

Full title

Early Cyst Growth Is Associated with the Increased Nuclear Expression of Cyclin D1/Rb Protein in an Autosomal-Recessive Polycystic Kidney Disease Rat Model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_878642548

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_878642548

Other Identifiers

ISSN

1660-8151

E-ISSN

2235-3186

DOI

10.1159/000320149

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