Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol
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Author / Creator
Yim, Harry , Haselbeck, Robert , Niu, Wei , Pujol-Baxley, Catherine , Burgard, Anthony , Boldt, Jeff , Khandurina, Julia , Trawick, John D , Osterhout, Robin E , Stephen, Rosary , Estadilla, Jazell , Teisan, Sy , Schreyer, H Brett , Andrae, Stefan , Yang, Tae Hoon , Lee, Sang Yup , Burk, Mark J and Van Dien, Stephen
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The design and implementation of a high-yielding enzymatic route to 1,4-butanediol—a compound not known to be produced naturally—provides a compelling example of how metabolic engineering can be harnessed for the microbial conversion of carbohydrate feedstocks to desired small molecules.
1,4-Butanediol (BDO) is an important commodity chemical us...
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Full title
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol
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TN_cdi_proquest_journals_879691575
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_879691575
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.580
