Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and p...
Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated [beta]-cell death
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Publisher
New York: American Diabetes Association
Journal title
Language
English
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Publisher
New York: American Diabetes Association
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Contents
OBJECTIVE--CD4 T-cells secreting interleukin (IL)-17 are implicated in several human autoimmune diseases, but their role in type 1 diabetes has not been defined. To address the relevance of such cells, we examined IL-17 secretion in response to [beta]-cell autoantigens, IL-17A gene expression in islets, and the potential functional consequences of...
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Full title
Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated [beta]-cell death
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TN_cdi_proquest_journals_884988997
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_884988997
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db10-1643
