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Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe...

Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_894705277

Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice

About this item

Full title

Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2011-10, Vol.91 (10), p.1459-1471

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Inflammation has a key role in diabetic nephropathy (DN) progression. Pentosan polysulfate (PPS) has been shown to decreases interstitial inflammation and glomerulosclerosis in 5/6 nephrectomized rats. Since PPS has an excellent long-term safety profile in interstitial cystitis treatment, and we recently found that old diabetic C57B6 mice develop D...

Alternative Titles

Full title

Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_894705277

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_894705277

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2011.93

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