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Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholder...

Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholder...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_898418761

Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei

About this item

Full title

Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.17165-17170

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Known mechanisms of resistance to β-lactam antibiotics include β-lactamase expression, altered drug target, decreased bacterial permeability, and increased drug efflux. Here, we describe a unique mechanism of β-lactam resistance in the biothreat organism Burkholderia pseudomallei (the cause of melioidosis), associated with treatment failure during...

Alternative Titles

Full title

Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_898418761

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_898418761

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1111020108

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