Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholder...
Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Known mechanisms of resistance to β-lactam antibiotics include β-lactamase expression, altered drug target, decreased bacterial permeability, and increased drug efflux. Here, we describe a unique mechanism of β-lactam resistance in the biothreat organism Burkholderia pseudomallei (the cause of melioidosis), associated with treatment failure during...
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Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei
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TN_cdi_proquest_journals_898418761
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_898418761
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1111020108