Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cance...
Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
To catalog protein-altering mutations that may drive the development of prostate cancers and their progression to metastatic disease systematically, we performed whole-exome sequencing of 23 prostate cancers derived from 16 different lethal metastatic tumors and three high-grade primary carcinomas. All tumors were propagated in mice as xenografts,...
Alternative Titles
Full title
Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_898419695
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_898419695
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1108745108
