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Glutamate dehydrogenase requirement for apoptosis induced by aristolochic acid in renal tubular epit...

Glutamate dehydrogenase requirement for apoptosis induced by aristolochic acid in renal tubular epit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_900906472

Glutamate dehydrogenase requirement for apoptosis induced by aristolochic acid in renal tubular epithelial cells

About this item

Full title

Glutamate dehydrogenase requirement for apoptosis induced by aristolochic acid in renal tubular epithelial cells

Publisher

Boston: Springer US

Journal title

Apoptosis (London), 2011-12, Vol.16 (12), p.1217-1228

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Ingestion of aristolochic acids (AA) contained in herbal remedies results in a renal disease and, frequently, urothelial malignancy. The genotoxicity of AA in renal cells, including mutagenic DNA adduct formation, is well-documented. However, the mechanisms of AA-induced tubular atrophy and renal fibrosis are largely unknown. Epithelial cell death...

Alternative Titles

Full title

Glutamate dehydrogenase requirement for apoptosis induced by aristolochic acid in renal tubular epithelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_900906472

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_900906472

Other Identifiers

ISSN

1360-8185

E-ISSN

1573-675X

DOI

10.1007/s10495-011-0646-5

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