Inflammasome activation and IL-1[Beta] target IL-1[alpha] for secretion as opposed to surface expres...
Inflammasome activation and IL-1[Beta] target IL-1[alpha] for secretion as opposed to surface expression
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Publisher
Washington: National Academy of Sciences
Journal title
Language
English
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Publisher
Washington: National Academy of Sciences
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Scope and Contents
Contents
Interleukin-1α (IL-1α) and -β both bind to the same IL-1 receptor (IL-1R) and are potent proinflammatory cytokines. Production of proinflammatory (pro)-IL-1α and pro-IL-1β is induced by Toll-like receptor (TLR)-mediated NF-...B activation. Additional stimulus involving activation of the inflammasome and caspase-1 is required for proteolytic cleavag...
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Full title
Inflammasome activation and IL-1[Beta] target IL-1[alpha] for secretion as opposed to surface expression
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TN_cdi_proquest_journals_902620988
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_902620988
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ISSN
0027-8424
E-ISSN
1091-6490
