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SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicit...

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_906339761

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

About this item

Full title

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2011-12, Vol.91 (12), p.1796-1804

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Recently, the SOX2 gene has been reported to be amplified in human lung squamous cell carcinomas. However, its roles in human lung adenocarcinomas are still elusive. In this study, we analyzed the functions of SOX2 in cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) derived from human lung adenocarcinoma. Human lung CSCs/CICs were isola...

Alternative Titles

Full title

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_906339761

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_906339761

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2011.140

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