Avascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours
Avascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours
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Beck, Benjamin , Driessens, Gregory , Goossens, Steven , Youssef, Khalil Kass , Kuchnio, Anna , Caauwe, Amélie , Sotiropoulou, Panagiota A , Loges, Sonja , Lapouge, Gaelle , Candi, Aurélie , Mascre, Guilhem , Drogat, Benjamin , Dekoninck, Sophie , Haigh, Jody J , Carmeliet, Peter and Blanpain, Cédric
Publisher
London: Nature Publishing Group
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English
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London: Nature Publishing Group
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Angiogenesis is critical during tumour initiation and malignant progression. Different strategies aimed at blocking vascular endothelial growth factor (VEGF) and its receptors have been developed to inhibit angiogenesis in cancer patients. It has become increasingly clear that in addition to its effect on angiogenesis, other mechanisms including a...
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Full title
Avascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours
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TN_cdi_proquest_journals_907243108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_907243108
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ISSN
0028-0836
E-ISSN
1476-4687