Analysis of Antiplatelet Effect of Ticlopidine In Humans: Modeling Based on Irreversible Inhibition...
Analysis of Antiplatelet Effect of Ticlopidine In Humans: Modeling Based on Irreversible Inhibition of Platelet Precursors in Bone Marrow
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New York: Springer Nature B.V
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English
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New York: Springer Nature B.V
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The relationship between plasma concentration of ticlopidine and its inhibitory effect on platelet aggregation in human was analyzed using a pharmacokinetic/pharmacodynamic (PK/PD) model. The data of plasma concentration and inhibitory effect on platelet aggregation were taken from the literature. A two-compartment open model was fitted to plasma t...
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Analysis of Antiplatelet Effect of Ticlopidine In Humans: Modeling Based on Irreversible Inhibition of Platelet Precursors in Bone Marrow
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TN_cdi_proquest_journals_916237057
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_916237057
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ISSN
1567-567X
E-ISSN
1573-8744
DOI
10.1023/A:1020995013200
