Vif hijacks CBF-[Beta] to degrade APOBEC3G and promote HIV-1 infection
Vif hijacks CBF-[Beta] to degrade APOBEC3G and promote HIV-1 infection
About this item
Full title
Author / Creator
Jäger, Stefanie , Kim, Dong Young , Hultquist, Judd F , Shindo, Keisuke , LaRue, Rebecca S , Kwon, Eunju , Li, Ming , Anderson, Brett D , Yen, Linda , Stanley, David , Mahon, Cathal , Kane, Joshua , Franks-Skiba, Kathy , Cimermancic, Peter , Burlingame, Alma , Sali, Andrej , Craik, Charles S , Harris, Reuben S , Gross, John D and Krogan, Nevan J
Publisher
London: Nature Publishing Group
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group
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Scope and Contents
Contents
Restriction factors, such as the retroviral complementary DNA deaminase APOBEC3G, are cellular proteins that dominantly block virus replication. The AIDS virus, human immunodeficiency virus type 1 (HIV-1), produces the accessory factor Vif, which counteracts the host's antiviral defence by hijacking a ubiquitin ligase complex, containing CUL5, ELOC...
Alternative Titles
Full title
Vif hijacks CBF-[Beta] to degrade APOBEC3G and promote HIV-1 infection
Authors, Artists and Contributors
Author / Creator
Kim, Dong Young
Hultquist, Judd F
Shindo, Keisuke
LaRue, Rebecca S
Kwon, Eunju
Li, Ming
Anderson, Brett D
Yen, Linda
Stanley, David
Mahon, Cathal
Kane, Joshua
Franks-Skiba, Kathy
Cimermancic, Peter
Burlingame, Alma
Sali, Andrej
Craik, Charles S
Harris, Reuben S
Gross, John D
Krogan, Nevan J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_921240212
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_921240212
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10693
