Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
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Author / Creator
Cabral, H. , Matsumoto, Y. , Mizuno, K. , Chen, Q. , Murakami, M. , Kimura, M. , Terada, Y. , Kano, M. R. , Miyazono, K. , Uesaka, M. , Nishiyama, N. and Kataoka, K.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
A major goal in cancer research is to develop carriers that can deliver drugs effectively and without side effects. Liposomal and particulate carriers with diameters of ∼100 nm have been widely used to improve the distribution and tumour accumulation of cancer drugs, but so far they have only been effective for treating highly permeable tumours. He...
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Full title
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
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TN_cdi_proquest_journals_921308106
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_921308106
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ISSN
1748-3387
E-ISSN
1748-3395
DOI
10.1038/nnano.2011.166