Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice
About this item
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Author / Creator
Ishimoto, Takuji , Lanaspa, Miguel A , Le, MyPhuong T , Garcia, Gabriela E , Diggle, Christine P , MacLean, Paul S , Jackman, Matthew R , Asipu, Aruna , Roncal-Jimenez, Carlos A , Kosugi, Tomoki , Rivard, Christopher J , Maruyama, Shoichi , Rodriguez-Iturbe, Bernardo , Sánchez-Lozada, Laura G , Bonthron, David T , Sautin, Yuri Y and Johnson, Richard J
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Fructose intake from added sugars correlates with the epidemic rise in obesity, metabolic syndrome, and nonalcoholic fatty liver disease. Fructose intake also causes features of metabolic syndrome in laboratory animals and humans. The first enzyme in fructose metabolism is fructokinase, which exists as two isoforms, A and C. Here we show that fruct...
Alternative Titles
Full title
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice
Authors, Artists and Contributors
Author / Creator
Lanaspa, Miguel A
Le, MyPhuong T
Garcia, Gabriela E
Diggle, Christine P
MacLean, Paul S
Jackman, Matthew R
Asipu, Aruna
Roncal-Jimenez, Carlos A
Kosugi, Tomoki
Rivard, Christopher J
Maruyama, Shoichi
Rodriguez-Iturbe, Bernardo
Sánchez-Lozada, Laura G
Bonthron, David T
Sautin, Yuri Y
Johnson, Richard J
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_928038942
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_928038942
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1119908109
