Wnt/[Beta]-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with...
Wnt/[Beta]-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
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Publisher
Washington: National Academy of Sciences
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Language
English
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Publisher
Washington: National Academy of Sciences
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Contents
Wnt binding to members of the seven-span transmembrane Frizzled (Fz) receptor family controls essential cell fate decisions and tissue polarity during development and in adulthood. The Fz-mediated membrane recruitment of the cytoplasmic effector Dishevelled (Dvl) is a critical step in Wnt/β-catenin signaling initiation, but how Fz and Dvl act toget...
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Full title
Wnt/[Beta]-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
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TN_cdi_proquest_journals_992993536
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_992993536
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ISSN
0027-8424
E-ISSN
1091-6490
