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Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II

Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1008829921

Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II

About this item

Full title

Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2370-2375

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The protein Vezf1 plays multiple roles important for embryonic development. In Vezf1⁻/⁻ mouse embryonic stem (mES) cells, our earlier data showed widespread changes in gene-expression profiles, including decreased expression of the full-length active isoform of Dnmt3b methyltransferase and concomitant genome-wide reduction in DNA methylation. Here...

Alternative Titles

Full title

Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1008829921

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1008829921

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1121538109

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