Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for d...
Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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RNA nanoparticles have applications in the treatment of cancers and viral infection; however, the instability of RNA nanoparticles has hindered their development for therapeutic applications. The lack of covalent linkage or crosslinking in nanoparticles causes dissociation
in vivo
. Here we show that the packaging RNA of bacteriophage phi29 D...
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Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics
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TN_cdi_proquest_miscellaneous_1008837066
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1008837066
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ISSN
1748-3387
E-ISSN
1748-3395
DOI
10.1038/nnano.2011.105