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Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for d...

Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1008837066

Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics

About this item

Full title

Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics

Publisher

London: Nature Publishing Group UK

Journal title

Nature nanotechnology, 2011-10, Vol.6 (10), p.658-667

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

RNA nanoparticles have applications in the treatment of cancers and viral infection; however, the instability of RNA nanoparticles has hindered their development for therapeutic applications. The lack of covalent linkage or crosslinking in nanoparticles causes dissociation
in vivo
. Here we show that the packaging RNA of bacteriophage phi29 D...

Alternative Titles

Full title

Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1008837066

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1008837066

Other Identifiers

ISSN

1748-3387

E-ISSN

1748-3395

DOI

10.1038/nnano.2011.105

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