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Long-term proliferation of functional human NK cells, with conversion of CD56(dim) NK cells to a CD5...

Long-term proliferation of functional human NK cells, with conversion of CD56(dim) NK cells to a CD5...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1010230151

Long-term proliferation of functional human NK cells, with conversion of CD56(dim) NK cells to a CD56 (bright) phenotype, induced by carcinoma cells co-expressing 4-1BBL and IL-12

About this item

Full title

Long-term proliferation of functional human NK cells, with conversion of CD56(dim) NK cells to a CD56 (bright) phenotype, induced by carcinoma cells co-expressing 4-1BBL and IL-12

Publisher

Germany

Journal title

Cancer immunology, immunotherapy, 2012-05, Vol.61 (5), p.615-628

Language

English

Formats

Publication information

Publisher

Germany

More information

Scope and Contents

Contents

4-1BB ligation co-stimulates T cell activation, and agonistic antibodies have entered clinical trials. Natural killer (NK) cells also express 4-1BB following activation and are implicated in the anti-tumour efficacy of 4-1BB stimulation in mice; however, the response of human NK cells to 4-1BB stimulation is not clearly defined. Stimulation of non-...

Alternative Titles

Full title

Long-term proliferation of functional human NK cells, with conversion of CD56(dim) NK cells to a CD56 (bright) phenotype, induced by carcinoma cells co-expressing 4-1BBL and IL-12

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1010230151

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1010230151

Other Identifiers

E-ISSN

1432-0851

DOI

10.1007/s00262-011-1122-3

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