Transcutaneous Gene Gun Delivery of hNC16A Induces BPAG2-Specific Tolerance
Transcutaneous Gene Gun Delivery of hNC16A Induces BPAG2-Specific Tolerance
About this item
Full title
Author / Creator
Publisher
New York, NY: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
New York, NY: Elsevier Inc
Subjects
More information
Scope and Contents
Contents
Immune recognition and rejection of tissues expressing transfected genes is a major complication of gene replacement therapy for inherited genetic disorders. Owing to the high immunogenicity of human bullous pemphigoid antigen 2 (hBPAG2), the induction and maintenance of tolerance to this neo-antigen is essential to deliver the gene product to pati...
Alternative Titles
Full title
Transcutaneous Gene Gun Delivery of hNC16A Induces BPAG2-Specific Tolerance
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1013921397
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1013921397
Other Identifiers
ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1038/jid.2012.19
