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Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis

Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1015098018

Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis

About this item

Full title

Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Journal of molecular medicine (Berlin, Germany), 2012-05, Vol.90 (5), p.597-608

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Cystic fibrosis (CF) is the most common lethal inherited disease in Caucasians and is caused by mutations in the
CFTR
gene. The disease is incurable and medical treatment is limited to the amelioration of symptoms or secondary complications. A comprehensive understanding of the disease mechanisms and the development of novel treatment options...

Alternative Titles

Full title

Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1015098018

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1015098018

Other Identifiers

ISSN

0946-2716

E-ISSN

1432-1440

DOI

10.1007/s00109-011-0839-y

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