Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis
Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis
About this item
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Author / Creator
Klymiuk, N. , Mundhenk, L. , Kraehe, K. , Wuensch, A. , Plog, S. , Emrich, D. , Langenmayer, M. C. , Stehr, M. , Holzinger, A. , Kröner, C. , Richter, A. , Kessler, B. , Kurome, M. , Eddicks, M. , Nagashima, H. , Heinritzi, K. , Gruber, A. D. and Wolf, E.
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Cystic fibrosis (CF) is the most common lethal inherited disease in Caucasians and is caused by mutations in the
CFTR
gene. The disease is incurable and medical treatment is limited to the amelioration of symptoms or secondary complications. A comprehensive understanding of the disease mechanisms and the development of novel treatment options...
Alternative Titles
Full title
Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis
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Record Identifier
TN_cdi_proquest_miscellaneous_1015098018
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1015098018
Other Identifiers
ISSN
0946-2716
E-ISSN
1432-1440
DOI
10.1007/s00109-011-0839-y