An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast canc...
An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer
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Author / Creator
Mamo, A , Cavallone, L , Tuzmen, S , Chabot, C , Ferrario, C , Hassan, S , Edgren, H , Kallioniemi, O , Aleynikova, O , Przybytkowski, E , Malcolm, K , Mousses, S , Tonin, P N and Basik, M
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Tumor-suppressor genes (TSGs) have been classically defined as genes whose loss of function in tumor cells contributes to the formation and/or maintenance of the tumor phenotype. TSGs containing nonsense mutations may not be expressed because of nonsense-mediated RNA decay (NMD). We combined inhibition of the NMD process, which clears transcripts t...
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Full title
An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer
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TN_cdi_proquest_miscellaneous_1017958692
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1017958692
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2011.386
