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Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects...

Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1022377568

Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects mice against challenge infection

About this item

Full title

Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects mice against challenge infection

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2012-07, Vol.30 (33), p.4971-4976

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights ► We describe an anti- sr HSP60 mAb that binds to Strongyloides ratti infective third stage larvae. ► Passive immunization with anti- sr HSP60 mAb protected mice from challenge infection. ► Protection was predominantly mediated by improved killing of migrating larvae.

Alternative Titles

Full title

Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects mice against challenge infection

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1022377568

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1022377568

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2012.05.046

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