Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects...
Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects mice against challenge infection
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Contents
Highlights ► We describe an anti- sr HSP60 mAb that binds to Strongyloides ratti infective third stage larvae. ► Passive immunization with anti- sr HSP60 mAb protected mice from challenge infection. ► Protection was predominantly mediated by improved killing of migrating larvae.
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Full title
Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects mice against challenge infection
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TN_cdi_proquest_miscellaneous_1022377568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1022377568
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2012.05.046