Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung met...
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
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More information
Scope and Contents
Contents
Intratumoral hypoxia, a frequent finding in metastatic cancer, results in the activation of hypoxia-inducible factors (HIFs). HIFs are implicated in many steps of breast cancer metastasis, including metastatic niche formation through increased expression of lysyl oxidase (LOX) and lysyl oxidase-like (LOXL) proteins, enzymes that remodel collagen at...
Alternative Titles
Full title
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
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Record Identifier
TN_cdi_proquest_miscellaneous_1022557758
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1022557758
Other Identifiers
ISSN
0946-2716
E-ISSN
1432-1440
DOI
10.1007/s00109-011-0855-y
