MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The kinase MPS1 is a conserved and essential component of the spindle assembly checkpoint (SAC), but its relevant substrate in this context has remained uncertain. Watanabe and colleagues now show that, in fission yeast and human cells, MPS1 (Mph1 in fission yeast) phosphorylates the kinetochore protein KNL1 (Spc7), leading to kinetochore recruitme...
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MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components
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TN_cdi_proquest_miscellaneous_1023293554
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1023293554
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1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2515
