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From genes to drugs: targeted strategies for melanoma

From genes to drugs: targeted strategies for melanoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1028025379

From genes to drugs: targeted strategies for melanoma

About this item

Full title

From genes to drugs: targeted strategies for melanoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2012-05, Vol.12 (5), p.349-361

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Oncogenic mutations in melanoma are increasingly well categorized and are not stand-alone events.
Several highly recurrent oncogenic mutations in melanoma occur within known signalling pathways. The most common of these is BRAF-V600E, which occurs in approximately 50% of melanomas.
Targeted therapies seek to inhibit functionally...

Alternative Titles

Full title

From genes to drugs: targeted strategies for melanoma

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1028025379

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1028025379

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/nrc3218

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