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Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion a...

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1034816519

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Patrick Tan, Bin Tean Teh, Steve Rozen and colleagues report recurrent somatic mutations in the cell-adhesion gene
FAT4
and the chromatin-remodeling gene
ARID1A
in gastric adenocarcinomas. Their data suggest that
FAT4
functions as a tumor suppressor by maintaining proper cell adhesion and preventing malignant cell migration.
Ga...

Alternative Titles

Full title

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1034816519

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1034816519

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.2246

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