Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencin...
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing
About this item
Full title
Author / Creator
Stark, Mitchell S , Woods, Susan L , Gartside, Michael G , Bonazzi, Vanessa F , Dutton-Regester, Ken , Aoude, Lauren G , Chow, Donald , Sereduk, Chris , Niemi, Natalie M , Tang, Nanyun , Ellis, Jonathan J , Reid, Jeffrey , Zismann, Victoria , Tyagi, Sonika , Muzny, Donna , Newsham, Irene , Wu, YuanQing , Palmer, Jane M , Pollak, Thomas , Youngkin, David , Brooks, Bradford R , Lanagan, Catherine , Schmidt, Christopher W , Kobe, Bostjan , MacKeigan, Jeffrey P , Yin, Hongwei , Brown, Kevin M , Gibbs, Richard , Trent, Jeffrey and Hayward, Nicholas K
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Nicholas Hayward and colleagues sequenced eight metastatic melanoma exomes and identified frequent somatic mutations in two MAP kinase family genes,
MAP3K5
and
MAP3K9
. Mutation in
MAP3K9
may confer resistance to temozolomide, a common chemotherapeutic drug.
We sequenced eight melanoma exomes to identify new somatic mutations i...
Alternative Titles
Full title
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing
Authors, Artists and Contributors
Author / Creator
Woods, Susan L
Gartside, Michael G
Bonazzi, Vanessa F
Dutton-Regester, Ken
Aoude, Lauren G
Chow, Donald
Sereduk, Chris
Niemi, Natalie M
Tang, Nanyun
Ellis, Jonathan J
Reid, Jeffrey
Zismann, Victoria
Tyagi, Sonika
Muzny, Donna
Newsham, Irene
Wu, YuanQing
Palmer, Jane M
Pollak, Thomas
Youngkin, David
Brooks, Bradford R
Lanagan, Catherine
Schmidt, Christopher W
Kobe, Bostjan
MacKeigan, Jeffrey P
Yin, Hongwei
Brown, Kevin M
Gibbs, Richard
Trent, Jeffrey
Hayward, Nicholas K
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1034819439
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1034819439
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.1041
