Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
About this item
Full title
Author / Creator
Wang, Kai , Kan, Junsuo , Yuen, Siu Tsan , Shi, Stephanie T , Chu, Kent Man , Law, Simon , Chan, Tsun Leung , Kan, Zhengyan , Chan, Annie S Y , Tsui, Wai Yin , Lee, Siu Po , Ho, Siu Lun , Chan, Anthony K W , Cheng, Grace H W , Roberts, Peter C , Rejto, Paul A , Gibson, Neil W , Pocalyko, David J , Mao, Mao , Xu, Jiangchun and Leung, Suet Yi
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Suet Leung, Jiangchun Xu and colleagues report exome sequencing of 22 gastric cancers. They found that genes involved in chromatin modification were commonly mutated, including
ARID1A
encoding an SWI/SNF chromatin-remodeling complex component that had a high rate of mutation.
Gastric cancer is a heterogeneous disease with multiple environm...
Alternative Titles
Full title
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
Authors, Artists and Contributors
Author / Creator
Kan, Junsuo
Yuen, Siu Tsan
Shi, Stephanie T
Chu, Kent Man
Law, Simon
Chan, Tsun Leung
Kan, Zhengyan
Chan, Annie S Y
Tsui, Wai Yin
Lee, Siu Po
Ho, Siu Lun
Chan, Anthony K W
Cheng, Grace H W
Roberts, Peter C
Rejto, Paul A
Gibson, Neil W
Pocalyko, David J
Mao, Mao
Xu, Jiangchun
Leung, Suet Yi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1034820703
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1034820703
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.982
